Impact of Diet and Lifestyle Modification on Obesity and Thyroid Symptom Severity in Adults with Hypothyroidism in Tobruk: A six -Month Pre–Post Study
- Authors
-
-
Hamdi Lemamsha
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor -
Gurch Randhawa
Institute for Health Research, University of Bedfordshire, Putteridge Bury Campus, Hitchin Road, Luton LU2 8LE, UKAuthor -
Retaj Najem
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor -
Retaaj Almabrouk
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor -
Amira Edries
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor -
Eman Abdalla
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor -
Amani Sulemen
Faculty of Medical Sciences, University of Tobruk, Tobruk, LibyaAuthor
-
- Keywords:
- Hypothyroidism; Obesity; Diet quality; Iodine intake; Lifestyle modification; Thyroid symptoms; Tobruk
- Abstract
-
Thyroid disorders and obesity are increasingly reported among adults in Libya, while evidence on structured diet and lifestyle support for symptom control remains limited, particularly in Tobruk. Current care often lacks integrated nutritional and behavioural guidance despite the growing endocrine and metabolic burden. This study examined the impact of diet and lifestyle modification on obesity and thyroid-related symptom severity among adults with hypothyroidism over six months. A quasi-experimental pre–post design with a non-equivalent comparison group was conducted at Tobruk Medical Center and Tobruk General Hospital. Thirty-two adults with hypothyroidism were equally allocated into an intervention group (n = 16) and a comparison group (n = 16). The intervention involved a six-month structured programme focusing on iodine-rich foods, improved diet quality, physical activity of at least 150 minutes per week, and adequate sleep of seven to nine hours per night. Data were collected using a structured questionnaire assessing thyroid symptom severity and four behavioural domains. Body weight and body mass index were recorded at baseline and follow-up. Analysis was conducted using Statistical Package for the Social Sciences version 28, including paired and independent t-tests, Pearson correlation, and regression analysis. The sample included twenty females and twelve males, mostly aged 35–54 years. Iodine-rich food intake showed a moderate negative correlation with thyroid symptom severity (r = −0.52, p < 0.001), while diet quality showed a stronger negative association (r = −0.59, p < 0.001). Physical activity and sleep showed non-significant associations (p > 0.05). Structured dietary modification may support better thyroid symptom control and obesity-related outcomes among adults with hypothyroidism in Tobruk
- Downloads
-
Download data is not yet available.
- Author Biographies
- References
-
Abuagela, M., Hakam, A., Abd-Alwafi, F., & Abuhalala, S. (2025). The effect of diet on the prevalence of thyroid disorder among Libyans. AlQalam Journal of Medical and Applied Sciences, 476–481.
Alkhatib, D., Shi, Z., & Ganji, V. (2024). Dietary patterns and hypothyroidism in US adult population. Nutrients, 16(3), 382. https://doi.org/10.3390/nu16030382
Amoore, B. Y., Gaa, P. K., Amalba, A., & Mogre, V. (2023). Nutrition education intervention improves medical students’ dietary habits and their competency and self-efficacy in providing nutrition care: A pre, post and follow-up quasi-experimental study. Frontiers in Nutrition, 10, 1063316. https://doi.org/10.3389/fnut.2023.1063316
Apovian, C. M., Aronne, L., & Barenbaum, S. R. (2023). Clinical management of obesity. Professional Communications, Inc.
Biondi, B. (2023). Subclinical hypothyroidism in patients with obesity and metabolic syndrome: A narrative review. Nutrients, 16(1), 87. https://doi.org/10.3390/nu16010087
Candussi, C. J., Bell, W., Thompson, A. S., Knüppel, S., Gaggl, M., Světnička, M., & Kühn, T. (2025). Risk of hypothyroidism in meat-eaters, fish-eaters, and vegetarians: A population-based prospective study. BMC Medicine, 23, 269. https://doi.org/10.1186/s12916-025-04045-7
Chiovato, L., Magri, F., & Carlé, A. (2019). Hypothyroidism in context: Where we’ve been and where we’re going. Advances in Therapy, 36(Suppl. 2), 47–58. https://doi.org/10.1007/s12325-019-01080-8
Christianson, A. (2025). The thyroid reset diet: Reverse hypothyroidism and Hashimoto’s symptoms with a proven iodine-balancing plan. Random House.
Drywień, M., Wątor, P., & Wojsiat, J. (2020). The importance of nutritional factors and dietary management of Hashimoto’s thyroiditis. Annals of Agricultural and Environmental Medicine, 27(2), 184–193. https://doi.org/10.26444/aaem/117508
Elhamroush, A. S., Faid, F., Eljamay, S. M., Eshtiweey, S. J., Adwebi, A. A., Dede, R. S., & Taher, B. I. B. (2024). Assessment of the Nutritional Status and Dietary Intake of Hemodialysis Patients. مجلة شمال إفريقيا للنشر العلمي (NAJSP), 34-50.
Goyal, N. (2026). Thyroid balance and holistic management: A complete integrative guide for hypothyroidism and Hashimoto’s thyroiditis. NGO Products.
Handley, M. A., Lyles, C. R., McCulloch, C., & Cattamanchi, A. (2018). Selecting and improving quasi-experimental designs in effectiveness and implementation research. Annual Review of Public Health, 39, 5–25.
Khan, S., Rehman, A., Zubair, M., & Khan, N. (2024). Exploring the link between obesity and hypothyroidism. Pakistan Journal of Health Sciences, 19–24. https://doi.org/10.54393/pjhs.v5i06.1554
Kohl, H. W., III, Murray, T. D., & Salvo, D. (2025). Foundations of physical activity and public health. Human Kinetics.
Kronenberg, H., Melmed, S., Polonsky, K., & Larsen, P. R. (2007). Principles of endocrinology. In H. Kronenberg, S. Melmed, K. Polonsky, & P. R. Larsen (Eds.), Williams textbook of endocrinology (11th ed., pp. 3–11). Saunders Elsevier.
Maciejewski, M. L. (2018). Quasi-experimental design. Biostatistics & Epidemiology. https://doi.org/10.1080/24709360.2018.1477468
Miller, C. J., Smith, S. N., & Pugatch, M. (2020). Experimental and quasi-experimental designs in implementation research. Psychiatry Research, 283, 112452.
Monaghan, L. F., Rich, E., & Bombak, A. E. (2022). Rethinking obesity: Critical perspectives in crisis times. Routledge.
Okosieme, O., Gilbert, J., Abraham, P., Boelaert, K., Dayan, C., Gurnell, M., & Vanderpump, M. (2016). Management of primary hypothyroidism: Statement by the British Thyroid Association Executive Committee. Clinical Endocrinology, 84(6), 799–808. https://doi.org/10.1111/cen.12824
Ostrowska, L., Gier, D., & Zyśk, B. (2021). The influence of reducing diets on changes in thyroid parameters in women suffering from obesity and Hashimoto’s disease. Nutrients, 13(3), 862. https://doi.org/10.3390/nu13030862
Rezaieg, N. S., & Awad, M. M. (2025). Impact of lifestyle modification on thyroid axis in obese adults: A quasi-experimental longitudinal study. Kirkuk Journal of Science, 20(4), 53–65. https://doi.org/10.32894/kujss.2025.165314.1249
Stroebe, W. (2022). Dieting, overweight and obesity: Self-regulation in a food-rich environment. Routledge.
Wu, K., Zhou, Y., Ke, S., Huang, J., Gao, X., Li, B., & Liu, L. (2021). Lifestyle is associated with thyroid function in subclinical hypothyroidism: A cross-sectional study. BMC Endocrine Disorders, 21, 112. https://doi.org/10.1186/s12902-021-00772-z
- Downloads
- Published
- 2026-05-26
- Issue
- Vol. 6 No. 2 (2026)
- Section
- Original Articles
- License
-
Copyright (c) 2026 Hamdi Lemamsha , Gurch Randhawa, Retaj Najem, Retaaj Almabrouk, Amira Edries, Eman Abdalla, Amani Sulemen (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Similar Articles
- Dr . Amal R. Agila, Ambarka Eid. H Kreim, Diet and Lifestyle on Blood Pressure Control among Hypertensive patients under care in Tripoli. , Derna Academy Journal for Applied Sciences: Vol. 2 No. 1 (2024)
- Nesreen Hossen, Yasmin Younas Sulayman , Khadeejah M.A. AL-Khurum, Prevalence of Thyroid Dysfunction in Children and Adolescents in Tobruk City, Libya , Derna Academy Journal for Applied Sciences: Vol. 5 No. 1 (2025)
- Tawfg Omar Abdlmola, Ali Guma Azbida, Esra Mosbah, Hana Fathi, Retag Nasser, Wedad Daw, Prevalence of Thyroid Disorders in Diabetic Patients in Tarhuna area , Derna Academy Journal for Applied Sciences: Vol. 1 No. 2 (2023)
- Aisha Ashammam, Amal Masri Iwhida, Dr. Omaro A. Aburas, Abtisam Miftah Dhaw, Emhamed Boras, The effect of peripheral neuropathy induced the Oxaliplatin in patients with colon cancer , Derna Academy Journal for Applied Sciences: Vol. 1 No. 1 (2023)
- Mumin S. I. J, Embarek, A. F. B., Influence of Storage Time and Packaging Type on the Quality of Wheat Verities , Derna Academy Journal for Applied Sciences: Vol. 2 No. 2 (2024)
- Abd Al-Salam Salem Masoud Al-Busaifi, A prospective Study to investigate the Prevalence of Vitamin D Deficiency Among Pregnant Women , Derna Academy Journal for Applied Sciences: Vol. 3 No. 1 (2025)
- Salem Zaed, Asfiedeen Saleh, Sara Ali , Mawada Dbdel Salam , Asmaa Idris , Danya Saeed , Nawal Misbah , Clinical Characteristics and Admission Patterns of Hospitalized Children in a Pediatric Department at Tobruk Medical Center: Retrospective Study , Derna Academy Journal for Applied Sciences: Vol. 6 No. 1 (2026)
- Fatalla Merjan Daboos, Eisa S Omar, Osama Muftah Ahmed, Antibiotic Susceptibility and Resistance Patterns of Staphylococcus aureus Isolated from Pus Samples in Tobruk Medical Center at Tobruk, Libya , Derna Academy Journal for Applied Sciences: Vol. 5 No. 1 (2025)
- Khadeejah Miftah Ali Al-Khurm, Rihab Othman Abdulrraziq , Mohammed Mansour Saeid, ( Withdrawn ) Prevalence of Vitamin D Deficiency Among School Children in Tobruk City, Libya , Derna Academy Journal for Applied Sciences: Vol. 4 No. 1 (2025)
- Magdi Mari Hassan , Weight Variation Test for Different Brands of Metformine 850mg Tablets , Derna Academy Journal for Applied Sciences: Vol. 5 No. 1 (2025)
You may also start an advanced similarity search for this article.



