The impact of Clostridium Difficile Infection in the UK hospitals

الملخص

Clostridioides difficile (C. difficile) is a bacterium responsible for causing severe diarrhea and more critical intestinal issues such as colitis. In the UK, C. difficile infections (CDI) are a major concern, especially within healthcare environments. Between April 2020 and March 2021, the annual rate of CDI was reported at 22.2 per 100,000 people, a number that has remained fairly consistent since 2013. C. difficile infections are commonly linked to the use of antibiotics, which can upset the natural balance of gut bacteria, allowing C. difficile to thrive. Older adults and individuals with weakened immune systems are particularly vulnerable. Effective infection prevention and control strategies, along with proper management of antibiotic use, are essential for controlling and decreasing the occurrence of CDI in the UK, another strain of the C. difficile appeared has been known as NAP1/027 has risen lately. This new strain tends to bring more serious infections. Hospitals are enforcing stringent infection prevention and control protocols to manage and lower CDI cases. Nevertheless, the rise of new, more aggressive strains and the bacteria's capacity to adapt to their surroundings necessitate ongoing vigilance and monitoring. This review will discuss Clostridium difficile problems in the UK hospitals from various aspects.