The Epidemiological Burden of Vitamin D Deficiency Among Males Across the Life Course: A Cross-Sectional Analytical Study
- Authors
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Mustafa Mohamed Drah
Faculty of Medical Science, University of Misrata, LibyaAuthor -
Fathia Eessa Faid
Faculty of Health Science, Nutrition Department, University of Misurata, Misurata, LibyaAuthor
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- Keywords:
- Vitamin D Deficiency, Males, Epidemiology, Age Groups, Public Health, Cross-Sectional Study
- Abstract
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Background: Vitamin D deficiency is a global public health concern, yet detailed epidemiological data focusing exclusively on males across all age groups remains limited in the Middle East and North Africa region. Objective: To determine the prevalence rate of vitamin D deficiency among males and analyze its variation across four main age categories. Methods: A descriptive cross-sectional study was conducted involving 868 males ranging from infants (0 years) to elderly (95 years). Serum 25-hydroxyvitamin D [25(OH)D] levels were measured and classified as: severe deficiency (<10 ng/mL), deficiency (10–<20 ng/mL), insufficiency (20–<30 ng/mL), and sufficiency (≥30 ng/mL). Results: The mean vitamin D level in the sample was 17.89 ± 12.52 ng/mL. Results showed an epidemic prevalence of deficiency, with clinical deficiency (<20 ng/mL) at 59.1% (*n* = 513), and 26.5% (*n* = 230) had severe deficiency (<10 ng/mL). The elderly group (≥65 years) was most affected, with a clinical deficiency rate of 64.5%, followed by children and adolescents (<18 years) at 59.4%. No statistically significant difference was found between age groups, χ² (3) = 2.85, *p* = .416. Conclusion: Vitamin D deficiency represents a substantial health burden affecting males at all life stages, with peak risk at both ends of the age spectrum. Findings call for comprehensive preventive strategies including food fortification and routine screening for males regardless of age.
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Al-Daghri, N. M., Al-Saleh, Y., Sabico, S., Aljohani, N., Al-Rubeaan, K., Al-Othman, A., & Chrousos, G. P. (2021). Vitamin D status of adult Saudi Arabian population: A national study. *International Journal of Environmental Research and Public Health, 18*(15), Article 8166. https://doi.org/10.3390/ijerph18158166.
Albakour, E. J., Eljamay, S. M., Faid, F. E., & Ibrahim, N. A. (2025). Vitamin D and Relationship with Cholesterol and Triglycerides. Indonesian Journal of Community Services, 4(2), 166-174.
Arabi, A., El Rassi, R., & El-Hajj Fuleihan, G. (2010). Hypovitaminosis D in developing countries—Prevalence, risk factors and outcomes. *Nature Reviews Endocrinology, 6*(10), 550–561. https://doi.org/10.1038/nrendo.2010.146
Bener, A., Al-Ansari, A. M., Zirie, M., & Al-Hamaq, A. O. (2018). Prevalence of vitamin D deficiency in Qatari population and its correlation with risk factors for type 2 diabetes mellitus: A cross-sectional survey. *Journal of Community Hospital Internal Medicine Perspectives, 8*(5), 260–266. https://doi.org/10.1080/20009666.2018.1523360
Cashman, K. D., Dowling, K. G., Škrabáková, Z., Gonzalez-Gross, M., Valtueña, J., De Henauw, S., & Kiely, M. (2016). Vitamin D deficiency in Europe: Pandemic? *The American Journal of Clinical Nutrition, 103*(4), 1033–1044. https://doi.org/10.3945/ajcn.115.120873.
Drah, M. M., & Eljamay, S. M. (2025). Exploring age-related patterns in vitamin D deficiency and gender variations. Derna Academy Journal for Applied Sciences, 3(1), 22-29.
El-Sharkawy, A. M., Agha, A. M., & El-Sharkawy, M. A. (2020). High prevalence of vitamin D deficiency among healthy Egyptian males: Relation to age and season. *The Aging Male, 23*(5), 1230–1237. https://doi.org/10.1080/13685538.2020.1761345.
Eljamay, S. M., Alghazali, M. A. A., & Eldalal, H. H. A. (2022). Incident of vitamin D deficiency in Derna CityLibya. J Endo Metabol Res, 3(1), 1-15.
Faaid, F. (2026). Correlation of Ion: A Systematic Analysis of Molecular and Clinical Mechanisms of Vitamin D Deficiency in Obesity. Derna Academy Journal for Applied Sciences, 6(2), 80-89.
Forrest, K. Y., & Stuhldreher, W. L. (2011). Prevalence and correlates of vitamin D deficiency in US adults. *Nutrition Research, 31*(1), 48–54. https://doi.org/10.1016/j.nutres.2010.12.001
Haq, A., Wimalawansa, S. J., Pludowski, P., & Anouti, F. A. (2018). Clinical practice guidelines for vitamin D in the United Arab Emirates. *The Journal of Steroid Biochemistry and Molecular Biology, 175*, 4–11. https://doi.org/10.1016/j.jsbmb.2017.09.009
Hilger, J., Friedel, A., Herr, R., Rausch, T., Roos, F., Wahl, D. A., & Hoffmann, K. (2014). A systematic review of vitamin D status in populations worldwide. *British Journal of Nutrition, 111*(1), 23–45. https://doi.org/10.1017/S0007114513001840
Holick, M. F. (2007). Vitamin D deficiency. *New England Journal of Medicine, 357*(3), 266–281. https://doi.org/10.1056/NEJMra070553
Holick, M. F., Binkley, N. C., Bischoff-Ferrari, H. A., Gordon, C. M., Hanley, D. A., Heaney, R. P., & Weaver, C. M. (2011). Evaluation, treatment, and prevention of vitamin D deficiency: An Endocrine Society clinical practice guideline. *The Journal of Clinical Endocrinology & Metabolism, 96*(7), 1911–1930. https://doi.org/10.1210/jc.2011-0385
Institute of Medicine. (2011). *Dietary reference intakes for calcium and vitamin D*. National Academies Press.
Lee, D. M., Tajar, A., Pye, S. R., Boonen, S., Vanderschueren, D., Bouillon, R., & O'Donnell, T. W. (2012). Association of hypogonadism with vitamin D status: The European Male Ageing Study. *European Journal of Endocrinology, 166*(1), 77–85. https://doi.org/10.1530/EJE-11-0433
Lips, P. (2001). Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Consequences for bone loss and fractures and therapeutic implications. *Endocrine Reviews, 22*(4), 477–501. https://doi.org/10.1210/edrv.22.4.0437
Lips, P., & van Schoor, N. M. (2011). The effect of vitamin D on bone and osteoporosis. *Best Practice & Research Clinical Endocrinology & Metabolism, 25*(4), 585–591. https://doi.org/10.1016/j.beem.2011.05.005
Mithal, A., Wahl, D. A., Bonjour, J. P., Burckhardt, P., Dawson-Hughes, B., Eisman, J. A., & Wolodkin, J. (2009). Global vitamin D status and determinants of hypovitaminosis D. *Osteoporosis International, 20*(11), 1807–1820. https://doi.org/10.1007/s00198-009-0954-6
Rabie, M. E., Al-Rubeaan, K., & Al-Shehri, A. (2019). Vitamin D deficiency in children and adolescents in the Middle East: A review. *Journal of Pediatric Endocrinology and Metabolism, 32*(10), 1043–1051. https://doi.org/10.1515/jpem-2019-0123
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- 2026-07-17
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- Vol. 7 No. 1 (2026)
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