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EVANS SYNDROME TRIGGERED BY COVID-19 INFECTION

Authors
  • Rudhuway Abdulqadir Mtawil

    Physiology Department, Tobruk Medical University, Tobruk
    Author
Keywords:
Evans syndrome, Autoimmune Cytopenia, COVID-19, Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, Hematology
Abstract

Evans syndrome is a rare autoimmune disorder characterized by the coexistence of autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP). The pathogenesis involves immune dysregulation leading to autoantibody-mediated destruction of multiple blood cell lineages. We report the case of a 40-year-old female presenting with jaundice, pancytopenia, hemodynamic instability, and serologically confirmed Evans syndrome associated with acute COVID-19 infection. The patient showed elevated AST and ALT, complete recovery after corticosteroid therapy, and has remained in remission for two years under regular follow-up.

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References

Aladily TN, Salama A. Autoimmune cytopenias in the context of COVID-19: mechanisms and management. Front Immunol. 2021;12:758514.

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Godeau B, Caulier MT, Decuypere L, et al. Evans syndrome in adults: clinical presentation and outcome. QJM. 2002;95(9):597–607.

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Michel M, Chanet V, Dechartres A, et al. The spectrum of Evans syndrome in adults: new insight into the disease based on the analysis of 68 cases. Blood. 2009;114(15):3167–3172.

Taherifard E, et al. COVID-19 associated Evans syndrome: A case report and review of the literature. Clin Case Rep. 2022;10(7):e06111.

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Published
2025-11-12
Section
Case Study

How to Cite

EVANS SYNDROME TRIGGERED BY COVID-19 INFECTION. (2025). Derna Academy Journal for Applied Sciences, 5(1), 50-52. https://doi.org/10.71147/49d6hw11

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